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Assay Detail

CHEMBL1061454

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Functional
Antioxidant activity assessed as inhibition of FeCl2-induced lipid peroxidation by thiocyanate method
18
Total Activities
18
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Potential antioxidants and tyrosinase inhibitors from synthetic polyphenolic deoxybenzoins.
Ng LT, Ko HH, Lu TM.
Bioorg Med Chem (2009) 17 : 4360 -4366
PubMed 19481947 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 18 4.92 6.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL563494 1 6.14
CHEMBL557103 1 5.74
CHEMBL557305 1 5.67
CHEMBL153 TROLOX 1 5.43
CHEMBL563589 1 5.21
CHEMBL550181 1 5.19
CHEMBL241858 ONONETIN 1 5.13
CHEMBL559867 1 4.97
CHEMBL560920 1 4.87
CHEMBL559473 1 4.68
CHEMBL552325 1 4.60
CHEMBL193200 1 4.59
CHEMBL551196 1 4.57
CHEMBL395753 1 4.43
CHEMBL196 ASCORBIC ACID 4.0 1 4.31
CHEMBL541247 1 4.07
CHEMBL555453 1 4.05
CHEMBL243376 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL563494 IC50 = 720.0 nM 6.14
CHEMBL557103 IC50 = 1840.0 nM 5.74
CHEMBL557305 IC50 = 2120.0 nM 5.67
CHEMBL153 TROLOX IC50 = 3680.0 nM 5.43
CHEMBL563589 IC50 = 6200.0 nM 5.21
CHEMBL550181 IC50 = 6470.0 nM 5.19
CHEMBL241858 ONONETIN IC50 = 7330.0 nM 5.13
CHEMBL559867 IC50 = 10690.0 nM 4.97
CHEMBL560920 IC50 = 13360.0 nM 4.87
CHEMBL559473 IC50 = 20840.0 nM 4.68
CHEMBL552325 IC50 = 24930.0 nM 4.60
CHEMBL193200 IC50 = 25530.0 nM 4.59
CHEMBL551196 IC50 = 27040.0 nM 4.57
CHEMBL395753 IC50 = 37420.0 nM 4.43
CHEMBL196 ASCORBIC ACID IC50 = 48520.0 nM 4.31
CHEMBL541247 IC50 = 85000.0 nM 4.07
CHEMBL555453 IC50 = 88380.0 nM 4.05
CHEMBL243376 IC50 = 178380.0 nM -