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Assay Detail

CHEMBL1062092

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of STAT3 by Western blotting
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Signal transducer and activator of transcription 3 (CHEMBL4026)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Cucurbitane-type triterpenoids from the stems of Cucumis melo.
Chen C, Qiang S, Lou L, Zhao W.
J Nat Prod (2009) 72 : 824 -829
PubMed 19348465 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL507237 CUCURBITACIN B 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL507237 CUCURBITACIN B IC50 = 3000.0 nM 5.52