Assay Detail
Binding
CHEMBL1065619
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Inhibition of FAAH-mediated [3H]AEA hydrolysis in rat brain homogenate by time-dependent studies
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.76 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL599617 | — | — | 1 | 6.80 |
| CHEMBL597562 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL599617 | — | Ki | = | 160.0 | nM | 6.80 |
| CHEMBL597562 | — | Ki | = | 190.0 | nM | 6.72 |