Assay Detail
Binding
CHEMBL1065624
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Inhibition of human recombinant MGL
6
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of paracetamol esters as novel fatty acid amide hydrolase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.37 | 5.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL599617 | — | — | 2 | 5.73 |
| CHEMBL597562 | — | — | 2 | 5.64 |
| CHEMBL591932 | — | — | 2 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL599617 | — | IC50 | = | 1862.09 | nM | 5.73 |
| CHEMBL599617 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL597562 | — | IC50 | = | 2290.87 | nM | 5.64 |
| CHEMBL597562 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL591932 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL591932 | — | IC50 | = | 18197.01 | nM | 4.74 |