Assay Detail
Functional
CHEMBL1065840
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Agonist activity at LPA3 expressed in human chem1 cells assessed as intracellular calcium mobilization by FLIPR assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | chem1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis, in vitro structure-activity relationship, and in vivo studies of 2-arylthiazolidine-4-carboxylic acid amides as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 2 | - | - |
| EC50 | 1 | 6.92 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL117021 | LYSOPHOSPHATIDIC ACID | — | 1 | 6.92 |
| CHEMBL234981 | — | — | 1 | - |
| CHEMBL361501 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL117021 | LYSOPHOSPHATIDIC ACID | EC50 | = | 120.0 | nM | 6.92 |
| CHEMBL234981 | — | Activity | - | — | - | |
| CHEMBL361501 | — | Activity | - | — | - |