Assay Detail
Binding
CHEMBL1066259
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Inhibition of human neutrophils gelatinase B after 30 mins by fluorescence plate reader
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.80 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL592228 | — | — | 1 | 5.64 |
| CHEMBL790 | CHLORHEXIDINE | 4.0 | 1 | 5.12 |
| CHEMBL592329 | — | — | 1 | 4.56 |
| CHEMBL592373 | — | — | 1 | 4.41 |
| CHEMBL290632 | PROCYANIDIN C1 | — | 1 | 4.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL592228 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL790 | CHLORHEXIDINE | IC50 | = | 7630.0 | nM | 5.12 |
| CHEMBL592329 | — | IC50 | = | 27300.0 | nM | 4.56 |
| CHEMBL592373 | — | IC50 | = | 39200.0 | nM | 4.41 |
| CHEMBL290632 | PROCYANIDIN C1 | IC50 | = | 53200.0 | nM | 4.27 |