Assay Detail
Binding
CHEMBL1067744
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Inhibition of TCPTP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 2 (CHEMBL3807) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.62 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL326115 | — | — | 1 | 7.62 |
| CHEMBL117869 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL326115 | — | Ki | = | 24.0 | nM | 7.62 |
| CHEMBL117869 | — | Ki | = | 164000.0 | nM | - |