Assay Detail
Functional
CHEMBL1068435
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Antagonist activity at AR by reporter gene assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Coumarins as novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for potential treatment of prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.76 | 5.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL592043 | — | — | 1 | 5.22 |
| CHEMBL589158 | — | — | 1 | 4.30 |
| CHEMBL589396 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL592043 | — | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL589158 | — | IC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL589396 | — | IC50 | - | — | - |