Assay Detail
Binding
CHEMBL1068515
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Binding affinity to thyroid receptor alpha
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Thyroid receptor agonists for the treatment of androgenetic alopecia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.18 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL608990 | — | — | 1 | 9.15 |
| CHEMBL594047 | — | — | 1 | 8.68 |
| CHEMBL594025 | — | — | 1 | 8.52 |
| CHEMBL594024 | — | — | 1 | 8.10 |
| CHEMBL125242 | — | — | 1 | 7.70 |
| CHEMBL596350 | — | — | 1 | 6.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL608990 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL594047 | — | Ki | = | 2.1 | nM | 8.68 |
| CHEMBL594025 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL594024 | — | Ki | = | 8.0 | nM | 8.10 |
| CHEMBL125242 | — | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL596350 | — | Ki | = | 126.0 | nM | 6.90 |