Assay Detail
Binding
CHEMBL1069075
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of 5HT1A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Molecular modeling study of 4-phenylpiperazine and 4-phenyl-1,2,3,6-tetrahydropyridine derivatives: a new step towards the design of high-affinity 5-HT1A ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.40 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL431367 | ROXINDOLE | 2.0 | 1 | 9.10 |
| CHEMBL130327 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL431367 | ROXINDOLE | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL130327 | — | IC50 | = | 20.0 | nM | 7.70 |