Assay Detail
Functional
CHEMBL1069608
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mouse PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | CV-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor alpha (CHEMBL2128) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Synthesis and biological activities of novel indole derivatives as potent and selective PPARgamma modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.26 | 5.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL602468 | — | — | 1 | 5.26 |
| CHEMBL601678 | — | — | 1 | - |
| CHEMBL1017 | TELMISARTAN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL602468 | — | EC50 | = | 5510.0 | nM | 5.26 |
| CHEMBL601678 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL1017 | TELMISARTAN | EC50 | > | 10000.0 | nM | - |