Assay Detail
ADMET
CHEMBL1073250
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP2C19
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.52 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL595632 | — | — | 1 | 4.52 |
| CHEMBL596515 | — | — | 1 | - |
| CHEMBL605833 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL595632 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL596515 | — | IC50 | < | 1000.0 | nM | - |
| CHEMBL605833 | — | IC50 | > | 30000.0 | nM | - |