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Assay Detail

CHEMBL1074616

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Binding
Binding affinity to soybean LO1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Glycine max
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Seed linoleate 13S-lipoxygenase-1 (CHEMBL4586)
Type SINGLE PROTEIN
Organism Glycine max

Publication

Substrate specificity effects of lipoxygenase products and inhibitors on soybean lipoxygenase-1.
Wecksler AT, Garcia NK, Holman TR.
Bioorg Med Chem (2009) 17 : 6534 -6539
PubMed 19716306 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.41 6.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL594396 OLEYL SULFATE 1 6.16
CHEMBL8659 OLEIC ACID 2.0 1 4.66

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL594396 OLEYL SULFATE Ki = 700.0 nM 6.16
CHEMBL8659 OLEIC ACID Ki = 22000.0 nM 4.66