Assay Detail
Functional
CHEMBL1099765
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Cytotoxicity against human ChaGo cells after 3 days by MTT assay
13
Total Activities
13
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | ChaGo |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Protoxylocarpins F-H, protolimonoids from seed kernels of Xylocarpus granatum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 11 | - | - |
| IC50 | 2 | 4.92 | 5.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1080141 | XYLOGRANATIN C | — | 1 | 5.04 |
| CHEMBL465423 | DEACETYLGEDUNIN | — | 1 | 4.80 |
| CHEMBL1075700 | PROTOXYLOCARPIN F | — | 1 | - |
| CHEMBL1075819 | — | — | 1 | - |
| CHEMBL1079490 | CHISOCHETON F | — | 1 | - |
| CHEMBL1081393 | PROCERANOLIDE | — | 1 | - |
| CHEMBL483006 | METHYLANGOLENSATE | — | 1 | - |
| CHEMBL1080142 | MEXICANOLIDE | — | 1 | - |
| CHEMBL1075722 | XYLOCCENSIN P | — | 1 | - |
| CHEMBL1075721 | XYLOCCENSIN O | — | 1 | - |
| CHEMBL1082138 | XYLOCENSIN K | — | 1 | - |
| CHEMBL1075702 | PROTOXYLOCARPIN H | — | 1 | - |
| CHEMBL1075701 | PROTOXYLOCARPIN G | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1080141 | XYLOGRANATIN C | IC50 | = | 9160.0 | nM | 5.04 |
| CHEMBL465423 | DEACETYLGEDUNIN | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL1075700 | PROTOXYLOCARPIN F | Activity | - | — | - | |
| CHEMBL1075819 | — | Activity | - | — | - | |
| CHEMBL1079490 | CHISOCHETON F | Activity | - | — | - | |
| CHEMBL1081393 | PROCERANOLIDE | Activity | - | — | - | |
| CHEMBL483006 | METHYLANGOLENSATE | Activity | - | — | - | |
| CHEMBL1080142 | MEXICANOLIDE | Activity | - | — | - | |
| CHEMBL1075722 | XYLOCCENSIN P | Activity | - | — | - | |
| CHEMBL1075721 | XYLOCCENSIN O | Activity | - | — | - | |
| CHEMBL1082138 | XYLOCENSIN K | Activity | - | — | - | |
| CHEMBL1075702 | PROTOXYLOCARPIN H | Activity | - | — | - | |
| CHEMBL1075701 | PROTOXYLOCARPIN G | Activity | - | — | - |