Assay Detail
ADMET
CHEMBL1100115
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Inhibition of CYP1A2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Benzimidazole Thumb Pocket I finger-loop inhibitors of HCV NS5B polymerase: improved drug-like properties through C-2 SAR in three sub-series.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.52 | 4.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL376487 | — | — | 1 | 4.52 |
| CHEMBL1077334 | — | — | 1 | 4.52 |
| CHEMBL1077335 | — | — | 1 | 4.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL376487 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL1077334 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL1077335 | — | IC50 | = | 30000.0 | nM | 4.52 |