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Assay Detail

CHEMBL1101970

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to rat brain CB2 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cannabinoid receptor 2 (CHEMBL2470)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Radiosynthesis of novel carbon-11-labeled triaryl ligands for cannabinoid-type 2 receptor.
Fujinaga M, Kumata K, Yanamoto K, Kawamura K, Yamasaki T, Yui J, Hatori A, Ogawa M, Yoshida Y, Nengaki N, Maeda J, Zhang MR.
Bioorg Med Chem Lett (2010) 20 : 1565 -1568
PubMed 20137936 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.10 9.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1076680 1 9.57
CHEMBL1081609 1 8.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1076680 Ki = 0.27 nM 9.57
CHEMBL1081609 Ki = 2.32 nM 8.63