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Assay Detail

CHEMBL1103394

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant GST-JNK3 after 120 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Mitogen-activated protein kinase 10 (CHEMBL2637)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small molecule JNK (c-Jun N-terminal kinase) inhibitors.
Siddiqui MA, Reddy PA.
J Med Chem (2010) 53 : 3005 -3012
PubMed 20146479 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.82 6.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL383955 1 6.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL383955 IC50 = 150.0 nM 6.82