Assay Detail
Binding
CHEMBL1103397
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Inhibition of p38alpha
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Small molecule JNK (c-Jun N-terminal kinase) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.08 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL198756 | — | — | 1 | 7.55 |
| CHEMBL383177 | — | — | 1 | 7.52 |
| CHEMBL199247 | — | — | 1 | 7.34 |
| CHEMBL1094013 | — | — | 1 | 7.27 |
| CHEMBL203535 | — | — | 1 | 6.75 |
| CHEMBL1092764 | — | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL198756 | — | IC50 | = | 28.0 | nM | 7.55 |
| CHEMBL383177 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL199247 | — | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL1094013 | — | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL203535 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL1092764 | — | IC50 | = | 903.0 | nM | 6.04 |