Assay Detail
Functional
CHEMBL1103519
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Antiviral activity against Influenza A virus Vietnam/1203/ 2004H/H5N1 infected MDCK cells after 42 to 46 hrs by neutral red dye uptake assay
4
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
(-)-Carbodine: enantiomeric synthesis and in vitro antiviral activity against various strains of influenza virus including H5N1 (avian influenza) and novel 2009 H1N1 (swine flu).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.41 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1089302 | — | — | 2 | 5.82 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 4.86 |
| CHEMBL1089502 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1089302 | — | EC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL1089302 | — | EC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 13900.0 | nM | 4.86 |
| CHEMBL1089502 | — | EC50 | > | 41000.0 | nM | - |