Assay Detail
Binding
CHEMBL1103919
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of c-Met-mediated scattering in HGF-stimulated human DU145 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of a novel series of potent RON receptor tyrosine kinase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.40 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL462232 | — | — | 1 | 7.10 |
| CHEMBL1094718 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL462232 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL1094718 | — | IC50 | = | 2000.0 | nM | 5.70 |