Assay Detail
Functional
CHEMBL1104268
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 3B-infected in human MT4 cells assessed as protection from virus-induced cytopathogenicity after 5 days by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.23 | 7.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1077031 | — | — | 1 | 7.44 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 7.43 |
| CHEMBL1077035 | — | — | 1 | 7.20 |
| CHEMBL1077036 | — | — | 1 | 7.20 |
| CHEMBL1077033 | — | — | 1 | 7.09 |
| CHEMBL1077034 | — | — | 1 | 7.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1077031 | — | IC50 | = | 36.0 | nM | 7.44 |
| CHEMBL140 | CURCUMIN | IC50 | = | 37.0 | nM | 7.43 |
| CHEMBL1077035 | — | IC50 | = | 63.0 | nM | 7.20 |
| CHEMBL1077036 | — | IC50 | = | 63.0 | nM | 7.20 |
| CHEMBL1077033 | — | IC50 | = | 81.0 | nM | 7.09 |
| CHEMBL1077034 | — | IC50 | = | 94.0 | nM | 7.03 |