Assay Detail
Functional
CHEMBL1104269
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV2 ROD infected in human MT4 cells assessed as protection from virus-induced cytopathogenicity after 5 days by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 2 |
| Cell Type | MT4 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 2 (CHEMBL380) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 2 |
Publication
Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.20 | 7.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 7.43 |
| CHEMBL1077031 | — | — | 1 | 7.34 |
| CHEMBL1077035 | — | — | 1 | 7.19 |
| CHEMBL1077036 | — | — | 1 | 7.16 |
| CHEMBL1077033 | — | — | 1 | 7.10 |
| CHEMBL1077034 | — | — | 1 | 6.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL140 | CURCUMIN | IC50 | = | 37.0 | nM | 7.43 |
| CHEMBL1077031 | — | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL1077035 | — | IC50 | = | 65.0 | nM | 7.19 |
| CHEMBL1077036 | — | IC50 | = | 69.0 | nM | 7.16 |
| CHEMBL1077033 | — | IC50 | = | 79.0 | nM | 7.10 |
| CHEMBL1077034 | — | IC50 | = | 107.0 | nM | 6.97 |