Assay Detail
Binding
CHEMBL1104713
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Inhibition of mouse recombinant iNOS
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.19 | 4.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL291627 | — | — | 1 | 4.19 |
| CHEMBL1099167 | — | — | 1 | 4.19 |
| CHEMBL1099168 | — | — | 1 | 4.19 |
| CHEMBL1099170 | — | — | 1 | 4.19 |
| CHEMBL1099171 | — | — | 1 | 4.19 |
| CHEMBL1099169 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL291627 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL1099167 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL1099168 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL1099170 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL1099171 | — | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL1099169 | — | IC50 | = | 135000.0 | nM | - |