Assay Detail
Binding
CHEMBL1105192
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of pig ALR1 assessed as decrease in NADPH absorbance by spectrophotometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Aldo-keto reductase family 1 member A1 (CHEMBL4049) ↗| Type | SINGLE PROTEIN |
| Organism | Sus scrofa |
Publication
Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.85 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL396176 | — | — | 1 | 5.27 |
| CHEMBL1076861 | — | — | 1 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL396176 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL1076861 | — | IC50 | = | 37000.0 | nM | 4.43 |