Assay Detail
Functional
CHEMBL1105499
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at recombinant GluA1 receptor expressed in Xenopus oocytes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | Oocyte |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.95 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1094977 | — | — | 1 | 6.58 |
| CHEMBL123132 | — | — | 1 | 6.42 |
| CHEMBL73698 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1094977 | — | EC50 | = | 260.0 | nM | 6.58 |
| CHEMBL123132 | — | EC50 | = | 380.0 | nM | 6.42 |
| CHEMBL73698 | — | EC50 | = | 14000.0 | nM | 4.85 |