Assay Detail
Functional
CHEMBL1105506
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at recombinant GluA1A2 receptor flop isoform expressed in Xenopus oocytes
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | Oocyte |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.78 | 4.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL73698 | — | — | 1 | 4.80 |
| CHEMBL575060 | GLUTAMIC ACID | 3.0 | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL73698 | — | EC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL575060 | GLUTAMIC ACID | EC50 | = | 18000.0 | nM | 4.75 |