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Assay Detail

CHEMBL1105508

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at recombinant GluA4 receptor flop isoform expressed in Xenopus oocytes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Cell Type Oocyte
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Developing a complete pharmacology for AMPA receptors: a perspective on subtype-selective ligands.
Fleming JJ, England PM.
Bioorg Med Chem (2010) 18 : 1381 -1387
PubMed 20096591 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 3 5.09 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL602962 1 5.77
CHEMBL575060 GLUTAMIC ACID 3.0 1 5.09
CHEMBL73698 1 4.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL602962 EC50 = 1700.0 nM 5.77
CHEMBL575060 GLUTAMIC ACID EC50 = 8100.0 nM 5.09
CHEMBL73698 EC50 = 39000.0 nM 4.41