Assay Detail
Functional
CHEMBL1105667
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Cytotoxicity against human NCI-H187 cells after 5 days by Resazurin Microplate Assay
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H187 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxicity against KB and NCI-H187 cell lines of modified flavonoids from Kaempferia parviflora.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 5.12 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1098028 | — | — | 1 | 7.85 |
| CHEMBL1087979 | — | — | 1 | 6.64 |
| CHEMBL1098362 | — | — | 1 | 5.63 |
| CHEMBL123 | ELLIPTECINE | — | 1 | 5.56 |
| CHEMBL1088111 | — | — | 1 | 5.39 |
| CHEMBL486009 | — | — | 1 | 5.01 |
| CHEMBL483550 | — | — | 1 | 4.60 |
| CHEMBL107131 | DIMETHYLPINOCEMBRIN | — | 1 | 4.48 |
| CHEMBL1087980 | — | — | 1 | 4.27 |
| CHEMBL399910 | PINOCEMBRIN | 2.0 | 1 | 4.02 |
| CHEMBL1088256 | — | — | 1 | 4.02 |
| CHEMBL1088513 | — | — | 1 | 4.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1098028 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL1087979 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL1098362 | — | IC50 | = | 2320.0 | nM | 5.63 |
| CHEMBL123 | ELLIPTECINE | IC50 | = | 2770.0 | nM | 5.56 |
| CHEMBL1088111 | — | IC50 | = | 4040.0 | nM | 5.39 |
| CHEMBL486009 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL483550 | — | IC50 | = | 25100.0 | nM | 4.60 |
| CHEMBL107131 | DIMETHYLPINOCEMBRIN | IC50 | = | 33060.0 | nM | 4.48 |
| CHEMBL1087980 | — | IC50 | = | 53190.0 | nM | 4.27 |
| CHEMBL399910 | PINOCEMBRIN | IC50 | = | 95530.0 | nM | 4.02 |
| CHEMBL1088256 | — | IC50 | = | 95560.0 | nM | 4.02 |
| CHEMBL1088513 | — | IC50 | = | 98230.0 | nM | 4.01 |