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Assay Detail

CHEMBL1106174

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Acinetobacter baumannii beta-lactamase OXA40
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Acinetobacter baumannii
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Beta-lactamase (CHEMBL1075159)
Type SINGLE PROTEIN
Organism Acinetobacter baumannii

Publication

4,7-Dichloro benzothien-2-yl sulfonylaminomethyl boronic acid: first boronic acid-derived beta-lactamase inhibitor with class A, C, and D activity.
Tan Q, Ogawa AM, Painter RE, Park YW, Young K, DiNinno FP.
Bioorg Med Chem Lett (2010) 20 : 2622 -2624
PubMed 20299220 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.25 5.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1089781 1 5.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1089781 IC50 = 5600.0 nM 5.25