Assay Detail
Functional
CHEMBL1107720
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Cytotoxicity against human CCRF-CEM cells after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure and cytotoxicity of arnamial and related fungal sesquiterpene aryl esters.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.57 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1078389 | ARNAMIAL | — | 1 | 5.05 |
| CHEMBL1078144 | MELLEDONAL C | — | 1 | 4.83 |
| CHEMBL1078142 | MELLEOLIDE D | — | 1 | 4.21 |
| CHEMBL1077563 | — | — | 1 | 4.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1078389 | ARNAMIAL | IC50 | = | 8910.0 | nM | 5.05 |
| CHEMBL1078144 | MELLEDONAL C | IC50 | = | 14750.0 | nM | 4.83 |
| CHEMBL1078142 | MELLEOLIDE D | IC50 | = | 61660.0 | nM | 4.21 |
| CHEMBL1077563 | — | IC50 | = | 63230.0 | nM | 4.20 |