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Assay Detail

CHEMBL1111169

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rat brain POP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Prolyl endopeptidase (CHEMBL4035)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors.
Lawandi J, Gerber-Lemaire S, Juillerat-Jeanneret L, Moitessier N.
J Med Chem (2010) 53 : 3423 -3438
PubMed 20058865 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.14 8.14

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL289651 1 8.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL289651 IC50 = 7.2 nM 8.14