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Assay Detail

CHEMBL1111490

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of AAK1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

AP2-associated protein kinase 1 (CHEMBL3830)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Selectively nonselective kinase inhibition: striking the right balance.
Morphy R.
J Med Chem (2010) 53 : 1413 -1437
PubMed 20166671 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.28 7.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL516312 1 7.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL516312 Kd = 53.0 nM 7.28