Assay Detail
Functional
CHEMBL1111548
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Cytotoxicity against human HCT116 cells after 72 hrs
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibition of eEF2-K by thieno[2,3-b]pyridine analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 4.49 | 4.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1092820 | — | — | 1 | 4.77 |
| CHEMBL1091829 | — | — | 1 | 4.72 |
| CHEMBL1091317 | — | — | 1 | 4.54 |
| CHEMBL1089006 | — | — | 1 | 4.42 |
| CHEMBL1094026 | — | — | 1 | 4.00 |
| CHEMBL1089956 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1092820 | — | EC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL1091829 | — | EC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL1091317 | — | EC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL1089006 | — | EC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL1094026 | — | EC50 | = | 100000.0 | nM | 4.00 |
| CHEMBL1089956 | — | EC50 | > | 100000.0 | nM | - |