Assay Detail
Binding
CHEMBL1114096
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Inhibition of bovine spleen PDE2 by surface plasmon resonance assay
9
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Tissue | Spleen |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Surface plasmon resonance-based detection of ladder-shaped polyethers by inhibition detection method.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.39 | 5.77 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1077121 | DESULFATED YESSOTOXIN | — | 2 | 5.77 |
| CHEMBL1077122 | BREVETOXIN | — | 1 | 5.75 |
| CHEMBL1077126 | YESSOTOXIN | — | 1 | 5.52 |
| CHEMBL500181 | — | — | 1 | 5.04 |
| CHEMBL1077119 | — | — | 1 | 4.89 |
| CHEMBL1088484 | — | — | 1 | - |
| CHEMBL1086786 | — | — | 1 | - |
| CHEMBL1077120 | SALINOMYCIN SODIUM | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1077121 | DESULFATED YESSOTOXIN | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL1077122 | BREVETOXIN | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL1077126 | YESSOTOXIN | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL500181 | — | IC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL1077119 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL1088484 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1086786 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL1077120 | SALINOMYCIN SODIUM | IC50 | > | 100000.0 | nM | - |
| CHEMBL1077121 | DESULFATED YESSOTOXIN | Inhibition | - | % | - |