Assay Detail
Functional
CHEMBL1114215
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against VSV infected in human HeLa cells assessed as protection from virus-induced cytopathogenicity after 1 to 2 days by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vesicular stomatitis virus |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Vesicular stomatitis virus (CHEMBL613739) ↗| Type | ORGANISM |
| Organism | Vesicular stomatitis virus |
Publication
Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 6.60 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1077034 | — | — | 1 | 7.96 |
| CHEMBL1077033 | — | — | 1 | 6.83 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 5.00 |
| CHEMBL1077031 | — | — | 1 | - |
| CHEMBL1077035 | — | — | 1 | - |
| CHEMBL1077036 | — | — | 1 | - |
| CHEMBL494759 | (S)-DHPA | — | 1 | - |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1077034 | — | EC50 | = | 11.0 | nM | 7.96 |
| CHEMBL1077033 | — | EC50 | = | 147.0 | nM | 6.83 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1077031 | — | EC50 | > | 82.0 | nM | - |
| CHEMBL1077035 | — | EC50 | > | 11.0 | nM | - |
| CHEMBL1077036 | — | EC50 | > | 119.0 | nM | - |
| CHEMBL494759 | (S)-DHPA | EC50 | = | 146000.0 | nM | - |
| CHEMBL140 | CURCUMIN | EC50 | > | 10.0 | nM | - |