Assay Detail
Functional
CHEMBL1114530
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of LPS-induced IL1-beta production in human whole blood by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Selective p38alpha inhibitors clinically evaluated for the treatment of chronic inflammatory disorders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1090089 | PAMAPIMOD | 2.0 | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1090089 | PAMAPIMOD | IC50 | = | 100.0 | nM | 7.00 |