Assay Detail
Functional
CHEMBL1115016
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Herpes simplex virus 2 G infected in HEL cells assessed as protection from virus-induced cytopathogenicity after 2 to 3 days by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 2 |
| Cell Type | HEL |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 6.03 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 8.00 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 7.52 |
| CHEMBL31634 | BRIVUDINE | 2.0 | 1 | 4.30 |
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 4.30 |
| CHEMBL1077034 | — | — | 1 | - |
| CHEMBL1077033 | — | — | 1 | - |
| CHEMBL1077031 | — | — | 1 | - |
| CHEMBL1077035 | — | — | 1 | - |
| CHEMBL1077036 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL140 | CURCUMIN | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL182 | GANCICLOVIR | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL31634 | BRIVUDINE | EC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 50000.0 | nM | 4.30 |
| CHEMBL1077034 | — | EC50 | > | 38.0 | nM | - |
| CHEMBL1077033 | — | EC50 | > | 147.0 | nM | - |
| CHEMBL1077031 | — | EC50 | > | 82.0 | nM | - |
| CHEMBL1077035 | — | EC50 | > | 11.0 | nM | - |
| CHEMBL1077036 | — | EC50 | > | 119.0 | nM | - |