Assay Detail
Binding
CHEMBL1117898
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Inhibition of PYK2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Emerging targets in osteoporosis disease modification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.34 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL472212 | — | — | 1 | 7.96 |
| CHEMBL1084546 | PF-00562271 | 1.0 | 1 | 7.85 |
| CHEMBL1084269 | — | — | 1 | 6.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL472212 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL1084546 | PF-00562271 | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL1084269 | — | IC50 | = | 637.0 | nM | 6.20 |