Assay Detail
ADMET
CHEMBL1118337
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Toxicity assessed as haemolysis in chicken RBC
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Gallus gallus |
| Cell Type | Erythrocyte |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of novel 1-phenyl-cycloalkane carbamides as potent and selective influenza fusion inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.81 | 6.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL114999 | — | — | 1 | 6.28 |
| CHEMBL1084735 | — | — | 1 | 5.66 |
| CHEMBL1082301 | — | — | 1 | 5.50 |
| CHEMBL1084978 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL114999 | — | IC50 | = | 530.0 | nM | 6.28 |
| CHEMBL1084735 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL1082301 | — | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL1084978 | — | IC50 | - | — | - |