Assay Detail
Functional
CHEMBL1120695
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Induction of osteogenesis in mouse MC3T3-E1 cells assessed as increase in osteoblast differentiation-associated ALP level
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | MC3T3-E1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Emerging targets in osteoporosis disease modification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.23 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL409538 | — | — | 1 | 7.40 |
| CHEMBL476459 | — | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL409538 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL476459 | — | EC50 | = | 90.0 | nM | 7.05 |