Assay Detail
ADMET
CHEMBL1121034
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Cytotoxicity against human CRL1634 cells after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.78 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1096804 | — | — | 1 | 4.92 |
| CHEMBL1094887 | — | — | 1 | 4.84 |
| CHEMBL36 | PYRIMETHAMINE | 4.0 | 1 | 4.79 |
| CHEMBL439 | SULFADIAZINE | 4.0 | 1 | 4.56 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1096804 | — | IC50 | = | 11900.0 | nM | 4.92 |
| CHEMBL1094887 | — | IC50 | = | 14500.0 | nM | 4.84 |
| CHEMBL36 | PYRIMETHAMINE | IC50 | = | 16100.0 | nM | 4.79 |
| CHEMBL439 | SULFADIAZINE | IC50 | = | 27300.0 | nM | 4.56 |