Assay Detail
Functional
CHEMBL1168565
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cell cycle arrest in mouse tsFT210 cells assessed as accumulation of cells at G2/M phase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | tsFT210 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Design and synthesis of spirotryprostatin-inspired diketopiperazine systems from prolyl spirooxoindolethiazolidine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.85 | 4.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL488302 | SPIROTRYPROSTATIN B | — | 1 | 4.85 |
| CHEMBL549475 | SPIROTRYPROSTATIN A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL488302 | SPIROTRYPROSTATIN B | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL549475 | SPIROTRYPROSTATIN A | IC50 | = | 197500.0 | nM | - |