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Assay Detail

CHEMBL1175285

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Functional
Cytotoxicity against mouse WEHI164 cells
5
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type WEHI-164
Confidence 1 — Organism
Curated By Autocuration

Target

WEHI-164 (CHEMBL614227)
Type CELL-LINE
Organism Mus musculus

Publication

Synthesis and cytotoxic activity of fluorinated analogues of Goniothalamus lactones. Impact of fluorine on oxidative processes.
Dumitrescu L, Mai Huong DT, Van Hung N, Crousse B, Bonnet-Delpon D.
Eur J Med Chem (2010) 45 : 3213 -3218
PubMed 20392543 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 5.07 5.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1170485 4 5.07
CHEMBL464443 GONIOTHALAMIN 1 5.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1170485 IC50 = 8500.0 nM 5.07
CHEMBL1170485 IC50 = 8500.0 nM 5.07
CHEMBL1170485 IC50 = 8500.0 nM 5.07
CHEMBL1170485 IC50 = 8500.0 nM 5.07
CHEMBL464443 GONIOTHALAMIN IC50 = 8500.0 nM 5.07