Assay Detail
ADMET
CHEMBL1217403
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Cytotoxicity against human Huh7.5 cells by celltiter-blue viability assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | Huh-7 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and anti-hepatitis C virus activity of novel ethyl 1H-indole-3-carboxylates in vitro.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.37 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1214598 | UMIFENOVIR | 3.0 | 1 | 6.00 |
| CHEMBL1214496 | — | — | 1 | 5.52 |
| CHEMBL1214551 | — | — | 1 | 5.52 |
| CHEMBL1214497 | — | — | 1 | 5.40 |
| CHEMBL1214548 | — | — | 1 | 5.40 |
| CHEMBL1214550 | — | — | 1 | 5.30 |
| CHEMBL1214552 | — | — | 1 | 5.30 |
| CHEMBL1214495 | — | — | 1 | 5.00 |
| CHEMBL1214549 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1214598 | UMIFENOVIR | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1214496 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1214551 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1214497 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1214548 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1214550 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL1214552 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL1214495 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL1214549 | — | IC50 | = | 12000.0 | nM | 4.92 |