Assay Detail
Binding
CHEMBL1217675
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Inhibition of tyrosinase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Identification of a potent and noncytotoxic inhibitor of melanin production.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.67 | 5.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL287556 | KOJIC ACID | — | 1 | 5.21 |
| CHEMBL537 | HYDROQUINONE | 4.0 | 1 | 4.12 |
| CHEMBL232202 | ARBUTIN | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL287556 | KOJIC ACID | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL537 | HYDROQUINONE | IC50 | = | 75000.0 | nM | 4.12 |
| CHEMBL232202 | ARBUTIN | IC50 | = | 17000000.0 | nM | - |