Assay Detail
Functional
CHEMBL1218830
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 3B/LA1 infected in human CD4+ T-cell assessed as inhibition of giant cell formation
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Long-lasting enfuvirtide carrier pentasaccharide conjugates with potent anti-human immunodeficiency virus type 1 activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 8.10 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL525076 | ENFUVIRTIDE | 4.0 | 1 | 8.52 |
| CHEMBL1213112 | — | — | 1 | 8.22 |
| CHEMBL1213080 | — | — | 1 | 7.89 |
| CHEMBL1213113 | — | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL525076 | ENFUVIRTIDE | EC50 | = | 3.0 | nM | 8.52 |
| CHEMBL1213112 | — | EC50 | = | 6.0 | nM | 8.22 |
| CHEMBL1213080 | — | EC50 | = | 13.0 | nM | 7.89 |
| CHEMBL1213113 | — | EC50 | = | 18.0 | nM | 7.75 |