Assay Detail
Functional
CHEMBL1220094
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Macacine herpesvirus 1 isolate MC1 infected in african green monkey Vero cells by plaque reduction assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Macacine alphaherpesvirus 1 |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Macacine alphaherpesvirus 1 (CHEMBL3301403) ↗| Type | ORGANISM |
| Organism | Macacine alphaherpesvirus 1 |
Publication
Inhibition of B virus (Macacine herpesvirus 1) by conventional and experimental antiviral compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.67 | 4.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | 4.0 | 1 | 4.71 |
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 4.71 |
| CHEMBL1090 | VIDARABINE | 4.0 | 1 | 4.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL184 | ACYCLOVIR | EC50 | = | 19300.0 | nM | 4.71 |
| CHEMBL182 | GANCICLOVIR | EC50 | = | 19300.0 | nM | 4.71 |
| CHEMBL1090 | VIDARABINE | EC50 | = | 26500.0 | nM | 4.58 |