Assay Detail
Functional
CHEMBL1225754
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against human OVCAR-3 cells after 48 hrs by SRB assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OVCAR-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New antitumoral agents I: In vitro anticancer activity and in vivo acute toxicity of synthetic 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one and derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.42 | 5.86 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL560131 | — | — | 1 | 5.86 |
| CHEMBL128729 | — | — | 1 | 5.66 |
| CHEMBL423698 | — | — | 1 | 5.63 |
| CHEMBL1224640 | — | — | 1 | 4.52 |
| CHEMBL1224641 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL560131 | — | IC50 | = | 1390.0 | nM | 5.86 |
| CHEMBL128729 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL423698 | — | IC50 | = | 2320.0 | nM | 5.63 |
| CHEMBL1224640 | — | IC50 | = | 30300.0 | nM | 4.52 |
| CHEMBL1224641 | — | IC50 | = | 115000.0 | nM | - |