Assay Detail
Functional
CHEMBL1226802
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human colon cancer cells after 24 hrs by MTS/PMS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Cancer cell lines |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.52 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL591429 | PAC-1 | 1.0 | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL591429 | PAC-1 | IC50 | = | 3.0 | nM | 8.52 |