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Assay Detail

CHEMBL1228545

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against HIV1 3B infected in human H9 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Cell Type H9
Confidence 1 — Organism
Curated By Autocuration

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Anti-AIDS agents 79. Design, synthesis, molecular modeling and structure-activity relationships of novel dicamphanoyl-2',2'-dimethyldihydropyranochromone (DCP) analogs as potent anti-HIV agents.
Zhou T, Shi Q, Chen CH, Zhu H, Huang L, Ho P, Lee KH.
Bioorg Med Chem (2010) 18 : 6678 -6689
PubMed 20728367 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 7.77 8.23

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1163200 1 8.23
CHEMBL269559 1 7.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1163200 EC50 = 5.9 nM 8.23
CHEMBL269559 EC50 = 49.0 nM 7.31